The Bioimaging and Sensing Center is committed to discovery, development and adaptation of cost-effective and intelligent sensors / sensing systems for biological applications (plants, animal & associated biological systems including safety/wellness of human systems). The center, founded in 1992, has conducted research projects with and for the the National Science Foundation, the U.S. Department of Agriculture, various crop grower associations, and private industry.

The Center for Biomedical Research at the University of North Dakota’s School of Medicine and Health Sciences is home to a state-of-the-art animal research facility.

The Center for Biopharmaceutical Research and Production performs market-driven research and develops biopharmaceuticals, including vaccines, to treat diseases. It was established in 2008 as a North Dakota Economic Development Center of Excellence to perform all aspects of biotechnology research and development, including basic science research, animal testing, human trials, product development, and manufacturing.

Founded in 1984, the Center for Innovation provides assistance to innovators, entrepreneurs, and researchers to launch new ventures, commercialize new technologies, and secure access to capital from private and public sources. The Center also manages two tech incubators in the UND Tech Park, provides SBIR outreach to the state's tech community, and has formed three angel networks in Grand Forks, Fargo and Bismarck.

North Dakota State University's Center of Excellence for Surface Protection provides access to world-class coatings and corrosion research expertise. The center performs economically significant and market-driven research and development with federal, state and private sector partners and collaborators. CSP staff capabilities include coatings, corrosion and surface protection. In addition, the Center can facilitate research projects with units across campus, leveraging a wide range of expertise that spans a broad range of disciplines.

CAEDM's mission includes spurring economic development in electronics, manufacturing and related disciplines. The center performs economically significant and market-driven research and development in electronics, software, chemistry, physics, coatings, polymeric materials and mechanical engineering with private sector partners and collaborators.

The Grand Forks Human Nutrition Research Center is one of six Human Nutrition Centers operated by the Agricultural Research Service of the United States Department of Agriculture. The Nutrition Center has numerous partnerships with universities, other government agencies as well as commodity groups. The 92,000-square-foot center contains state-of-the-art facilities for research with humans and animals, and multiple chemical and biochemical laboratories.

NRI conducts and supports clinical research to develop creative, innovative approaches to the care of patients with diseases of the brain. The Institute funds and manages projects which draw together scientists from the University of North Dakota and North Dakota State University with physicians practicing in the Red River Valley.

The UND Research Foundation’s REAC park, home to the Center of Excellence in Life Sciences and Advanced Technologies, provides space for high-tech businesses to set up shop, grow and build production operations nearby. REAC-1, the park’s first state-of-the-art facility, is currently home to several private-sector companies conducting research and development activities.

The NDSCS Skills & Technology Training Center works with private partners, helping them bridge the gap between their training needs and delivered services. STTC provides customized training and workforce development services, either at STTC or on-site. STTC was founded in 1997 provide a workforce Training Center for business and industry in the Fargo-Moorhead and surrounding area.

The University of North Dakota (UND) Computational Research Center (CRC) is dedicated to helping researchers affiliated with the University of North Dakota solve increasingly challenging problems in science and society. By supporting high performance computing hardware, software, and staff through the Division of Research, the University provides quality computing resources to researchers and faculty involved in creative activities which require intricate numerical modeling and data-intensive simulations.